Cheng-Hung Tsai

I am a Bioinformatician and Computational Biologist with a Ph.D. from UC Riverside, specializing at the intersection of evolutionary biology, large-scale genomics, and high-performance software engineering.

My research leverages computational algorithms and statistical methods to investigate genome evolution, structural variation, and microbial diversity across comparative genomics and metagenomics datasets. In parallel, I develop and apply machine learning and deep learning models to predict regulatory features and analyze complex epigenomic patterns. I am passionate about engineering open-source bioinformatics software and automated workflows that scale seamlessly from local workstations to high-performance computing (HPC) clusters.

Having started my career at the bench in molecular biology before transitioning to computational research, I design software with a practical understanding of both the underlying biology and the data it produces.